👤 Chibuzor Olelewe

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Serum-Stable Gold(III) Bisphosphine Complex Induces Mild Mitochondrial Uncoupling and In Vivo Antitumor Potency in Triple Negative Breast Cancer

Adedamola S. Arojojoye, Chibuzor Olelewe, Sailajah Gukathasan +5 more · 2023 · Journal of Medicinal Chemistry · ACS Publications · added 2026-04-20
TLDR: To the best of the knowledge, Au-3 is the first biphenyl gold-phosphine complex to uncouple mitochondria and inhibit TNBC growth in vivo.
no PDF DOI: 10.1021/acs.jmedchem.3c00238 📎 SI
Au anticancer mitochondria