👤 N Gautham

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D Bharanidharan, S Thiyagarajan, N Gautham · 2007 · Acta crystallographica. Section F, Structural biology and crystallization communications · added 2026-04-20
The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the Show more
The hexamer duplex d(CGCGCA).d(TGCGCG) was crystallized with hexammineruthenium(III) ions in an orthorhombic space group; the crystals diffracted to 1.54 A resolution. Strong ion interactions with the adenine base induce a tautomeric shift from the amino to the imino form. Consequently, the A.T base pairing is disrupted. This structural study may be relevant to metal toxicity. Show less
no PDF DOI: 10.1107/S1744309107047781
adenine amine base pairing disruption bioinorganic coordination chemistry dna hexammineruthenium(iii) ru