Novel bis-C,N-cyclometalated iridium(III) thiosemicarbazide antitumor complexes: interactions with human serum albumin and DNA, and inhibition of cathepsin B.

ULTRA-HIGH DYNAMIC RANGE Monolithic Amplifier 50Ω PGA-1021+ 0.05 to 6 GHz THE BIG DEAL y +3.3 V, 57 mA Operation y High IP3, +26.7 dBm Typ. at 2 GHz y Gain, 13.4 dB Typ. at 2 GHz y P1dB +16.9 dBm Typ. at 2 GHz y Low Noise Figure, 2.4 dB at 2 GHz y No External Matching Components Required Generic photo used for illustration purposes only CASE STYLE: DF782 APPLICATIONS y Base Station Infrastructure y Portable Wireless y CATV & DBS y MMDS & Wireless LAN y LTE PRODUCT OVERVIEW PGA-1021+ (RoHS compliant) is an advanced wideband amplifier fabricated using E-pHEMT technology and offers extremely high dynamic range over a broad frequency range and with low noise figure. In addition, the PGA-1021+ has good input and output return loss over a broad frequency range without the need for external matching components and has demonstrated excellent reliability. Lead finish is SnAgNi. It has repeatable performance from lot to lot and is enclosed in a SOT-89 package for very good thermal performance. KEY FEATURES Feature Broad Band: 0.05 to 6.0 GHz High IP3 Versus DC Power Consumption: +26.7 dBm Typical at 2 GHz at +3.3 V Supply Voltage and Only 83 mA Advantages Broadband covering primary wireless communications bands: Cellular, PCS, LTE, WiMAX The PGA-1021+ provides good IP3 performance relative to device size and power consumption. The combination of the design and E-pHEMT Structure provides enhanced linearity over a broad frequency range as evidenced in the IP3 being typically 15 dB above the P1dB point. This feature makes this amplifier ideal for use in: y Driver amplifiers for complex waveform up converter paths y Drivers in linearized transmit systems y Secondary amplifiers in ultra High Dynamic range receivers No External Matching Components Required Unlike competing products, Mini-Circuits PGA-1021+ provides Input and Output Return Loss of 15-21 dB up to 4 GHz without the need for any external matching components. However, an external resistor, R1=2.37kΩ is used for biasing (See Figure 2). Low Noise Figure: 2.4 dB at 2 GHz A unique feature of the PGA-1021+ which separates this design from all competitors is the low noise figure performance in combination with the high dynamic range. REV. D ECO-024506 PGA-1021+ MCL NY 250212 www.minicircuits.com P.O. Box 350166, Brooklyn, NY 11235-0003 (718) 934-4500 sales@minicircuits.com PAGE 1 OF 2 ULTRA-HIGH DYNAMIC RANGE Monolithic Amplifier 50Ω PGA-1021+ 0.05 to 6 GHz ELECTRICAL SPECIFICATIONS1 AT +25°C, 50Ω AND +3.3 V, UNLESS NOTED OTHERWISE Parameter Condition (GHz) Frequency Range Min. Typ. 0.05 0.05 0.8 2.0 3.0 4.0 6.0 0.05 0.8 2.0 3.0 4.0 6.0 0.05 0.8 2.0 3.0 4.0 6.0 2.0 0.05 0.8 2.0 3.0 4.0 6.0 0.05 0.8 2.0 3.0 4.0 6.0 0.05 0.8 2.0 3.0 4.0 6.0 Gain Input Return Loss Output Return Loss Reverse Isolation Output Power @ 1 dB Compression Output IP3 Noise Figure Device Operating Voltage Device Operating Current Device Current Variation vs. Temperature Device Current Variation vs. Voltage Thermal Resistance, Junction-to-Ground Lead 13.6 13.0 18.0 +14.8 +3.1 37 16.9 15.1 13.4 11.9 11.0 9.8 12.1 16.6 11.7 9.8 8.6 6.2 15.5 25.4 19.3 16.4 14.5 10.6 21.2 +16.8 +16.8 +16.9 +16.9 +16.6 +15.9 +26.3 +26.5 +26.7 +27.0 +27.7 +27.3 2.1 2.3 2.4 2.9 3.1 3.8 +3.3 57 29 0.066 73 Max. Units 6 GHz 17.2 dB dB dB dB dBm dBm dB +3.5 90 V mA µA/°C mA/mV °C/W 1. Measured on Mini-Circuits Characterization test board TB-313 with external biasing resistor (2.37kΩ) and Bias-Tee. See Characterization Test Circuit (Fig. 1). ABSOLUTE MAXIMUM RATINGS2 Parameter Ratings Operating Temperature (Ground Lead) -40°C to +85°C Storage Temperature -65°C to +150°C Operating Current at +3.3 V 300 mA Power Dissipation 1.0 W Input Power (CW) +28 dBm DC Voltage on Pin 3 +5.5 V 2. Permanent damage may occur if any of these limits are exceeded. Electrical maximum ratings are not intended for continuous normal operation. www.minicircuits.com P.O. Box 350166, Brooklyn, NY 11235-0003 (718) 934-4500 sales@minicircuits.com PAGE 2 OF 2 ULTRA-HIGH DYNAMIC RANGE Monolithic Amplifier 50Ω PGA-1021+ 0.05 to 6 GHz SIMPLIFIED SCHEMATIC AND PIN DESCRIPTION RF-OUT and DC-IN RF-IN 3 RF-OUT & DC-IN 4 2 GROUND 1 RF-IN GND Function Pin Number Description RF-IN 1 RF input pin. This pin requires the use of an external DC blocking capacitor chosen for the frequency of operation. RF-OUT and DC-IN 3 RF output and bias pin. DC voltage is present on this pin; therefore a DC blocking capacitor is necessary for proper operation. An RF choke is needed to feed DC bias without loss of RF signal due to the bias connection, as shown in “Recommended Application Circuit”, Fig. 2. GND 2,4 Connections to ground. Use via holes as shown in “Suggested Layout for PCB Design” to reduce ground path inductance for best performance. CHARACTERIZATION TEST CIRCUIT 2.37 kΩ Vcc (supply Voltage) 1 RF-IN Bias-Tee ZX85-12G-S+ 3 2,4 DUT TB-313 +3.3V RF-OUT Bias-Tee ZX85-12G-S+ Fig 1. Block Diagram of Test Circuit used for characterization. (DUT tested on Mini-Circuits Characterization test board TB-313) Gain, Return Loss, Output Power at 1 dB Compression (P1 dB), Output IP3 (OIP3) and Noise Figure measured using Agilent’s N5242A PNA-X microwave network analyzer. Conditions: 1. Gain and Return loss: PIN= -25 dBm 2. Output IP3 (OIP3): Two tones, spaced 10 MHz apart, 0 dBm/tone at output. www.minicircuits.com P.O. Box 350166, Brooklyn, NY 11235-0003 (718) 934-4500 sales@minicircuits.com PAGE 3 OF 4 ULTRA-HIGH DYNAMIC RANGE Monolithic Amplifier 50Ω PGA-1021+ 0.05 to 6 GHz RECOMMENDED APPLICATION CIRCUIT Vcc Cbypass Ibias 4 Cblok 1 IN 3 OUT Vd R1 2 BIAS-TEE R1=2.37kΩ, Cblock=0.001 µF, Bias-Tee=TCBT-14+, Cbypass=0.1 µF Fig 2. Evaluation board includes case, connectors, and components soldered to PCB PRODUCT MARKING PGA1 Marking may contain other features or characters for internal lot control. www.minicircuits.com P.O. Box 350166, Brooklyn, NY 11235-0003 (718) 934-4500 sales@minicircuits.com PAGE 4 OF 4 ULTRA-HIGH DYNAMIC RANGE Monolithic Amplifier 50Ω PGA-1021+ 0.05 to 6 GHz ADDITIONAL DETAILED TECHNICAL INFORMATION IS AVAILABLE ON OUR DASHBOARD. CLICK HE RE Data Table Performance Data Swept Graphs S-Parameter (S2P Files) Data Set (.zip file) Case Style DF782 (SOT 89) Plastic package, exposed paddle lead finish: tin-silver over nickel Tape & Reel Standard Quantities Available on Reel F55 7” Reels with 20, 50, 100, 200, 500 or 1K devices Suggested Layout for PCB Design PL-313 Evaluation Board TB-596-2+ Environmental Ratings ENV08T1 ESD RATING Human Body Model (HBM): Class 1B (500 to <1000 V) in accordance with ANSI/ESD STM 5.1 - 2001 Machine Model (MM): Class M1(50 V) in accordance with ANSI/ESD STM5.2-1999 MSL RATING Moisture Sensitivity: MSL1 in accordance with IPC/JEDEC J-STD-020D Attention Observe precautions for handling electrostatic sensitive devices MSL TEST FLOW CHART Visual Inspection Electrical Test SAM Analysis Reflow 3 cycles 260°C Soak 85°C/85RH 168 hours Bake at 125°C, 24 hours Visual Inspection Electrical Test SAM Analysis Start Finish NOTES A. Performance and quality attributes and conditions not expressly stated in this specification document are intended to be excluded and do not form a part of this specification document. B. Electrical specifications and performance data contained in this specification document are based on Mini-Circuit’s applicable established test performance criteria and measurement instructions. C. The parts covered by this specification document are subject to Mini-Circuits standard limited warranty and terms and conditions (collectively, “Standard Terms”); Purchasers of this part are entitled to the rights and benefits contained therein. For a full statement of the standard terms and the exclusive rights and remedies thereunder, please visit Mini-Circuits’ website at www.minicircuits.com/terms/viewterm.html www.minicircuits.com P.O. Box 350166, Brooklyn, NY 11235-0003 (718) 934-4500 sales@minicircuits.com PAGE 5 OF 5