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Ionic Ruthenium and Iron Based Complexes Bearing Silver Containing Anions as a Potent New Class of Anticancer Agents
List of publications
December 2024
biocrates.com
biocrates-List
of publications
(Q4-2024)
biocrates-List
of publications
(Q4-2024)
For research
use only
| not| not
forfor
use
procedures
For research
use only
useinindiagnostic
diagnostic procedures
page 1
List of publications
January 2021 – December 2024
List of publications ......................................................................................................... 2
1
Cardiometabolic diseases ......................................................................................... 3
1.1
Cardiology .............................................................................................................. 3
1.2
Diabetology ............................................................................................................. 7
1.3
Hepatology ........................................................................................................... 13
1.4
Nephrology ........................................................................................................... 18
2
Neuroscience ........................................................................................................ 20
3
Nutrition and lifestyle ............................................................................................. 30
4
Oncology .............................................................................................................. 41
5
Pharmacology and toxicology ................................................................................. 49
6
Others .................................................................................................................. 56
6.1
Aging .................................................................................................................... 57
6.2
Animal health ........................................................................................................ 60
6.3
Endocrinology and fertility ..................................................................................... 66
6.4
Epidemiology and genetics .................................................................................... 69
6.5
Gastroenterology................................................................................................... 78
6.6
Gynecology and obstetrics ..................................................................................... 80
6.7
Infectiology ........................................................................................................... 82
6.8
Inflammation and immunology ............................................................................... 86
6.9
Methodology ......................................................................................................... 92
6.10 Microbiome ........................................................................................................... 95
6.11 Pulmonology ....................................................................................................... 100
Ordering ................................................................................................................... 103
biocrates-List of publications (Q4-2024)
For research use only | not for use in diagnostic procedures
page 2
1
Cardiometabolic diseases
2024
Ponce-de-Leon M, Wang-Sattler R, Peters A, Rathmann W, Grallert H, Artati A et al. Stool and
blood metabolomics in the metabolic syndrome: a cross-sectional study. Metabolomics 2024;
20(5):105. DOI: 10.1007/s11306-024-02166-3.
1.1
Cardiology
2024
Andrews SG, Koehle AM, Paudel D, Neuberger T, Ross AC, Singh V et al. Diet-Induced Severe
Hyperhomocysteinemia Promotes Atherosclerosis Progression and Dysregulates the Plasma
Metabolome in Apolipoprotein-E-Deficient Mice. Nutrients 2024; 16(3):330
DOI: 10.3390/nu16030330.
Castro R, Kalecký K, Huang NK, Petersen K, Singh V, Ross AC et al. A very-low carbohydrate
content in a high-fat diet modifies the plasma metabolome and impacts systemic inflammation
and experimental atherosclerosis. The Journal of Nutritional Biochemistry 2024; 126:109562
DOI: 10.1016/j.jnutbio.2023.109562.
Cho S, Dadson K, Sung HK, Ayansola O, Mirzaesmaeili A, Noskovicova N et al. Cardioprotection
by the adiponectin receptor agonist ALY688 in a preclinical mouse model of heart failure with
reduced ejection fraction (HFrEF). Biomed Pharmacother 2024; 171:116119
DOI: 10.1016/j.biopha.2023.116119.
Decker NS, Johnson T, Le Cornet C, Behrens S, Obi N, Kaaks R et al. Associations between
lifestyle, health, and clinical characteristics and circulating oxysterols and cholesterol
precursors in women diagnosed with breast cancer: a cross-sectional study. Sci Rep 2024;
14(1):4977 DOI: 10.1038/s41598-024-55316-x.
Hannemann A, Ameling S, Lehnert K, Dörr M, Felix SB, Nauck M et al. Integrative Analyses of
Circulating Proteins and Metabolites Reveal Sex Differences in the Associations with Cardiac
Function among DCM Patients. IJMS 2024; 25(13):6827 DOI: 10.3390/ijms25136827.
Kovácsházi C, Hambalkó S, Sayour NV, Gergely TG, Brenner GB, Pelyhe C et al. Effect of
hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles. Sci Rep
2024; 14(1):12016 DOI: 10.1038/s41598-024-62689-6.
Kretzschmar T, Westphal J, Neugebauer S, Wu JMF, Zeller M, Bogoviku J et al. Metabolic
Profiling Identifies 1-MetHis and 3-IPA as Potential Diagnostic Biomarkers for Patients With
Acute and Chronic Heart Failure With Reduced Ejection Fraction. Circ Heart Fail 2024;
17(1):e010813 DOI: 10.1161/CIRCHEARTFAILURE.123.010813.
Maushagen J, Addin NS, Schuppert C, Ward-Caviness CK, Nattenmüller J, Adamski J et al. Serum
metabolite signatures of cardiac function and morphology in individuals from a populationbased cohort. Biomark Res 2024; 12(1):31 DOI: 10.1186/s40364-024-00578-w.
biocrates-List of publications (Q4-2024)
For research use only | not for use in diagnostic procedures
page 3
Roessler J, Zimmermann F, Schumann P, Nageswaran V, Ramezani Rad P, Schuchardt S et al.
Modulation of the Serum Metabolome by the Short-Chain Fatty Acid Propionate: Potential
Implications for Its Cholesterol-Lowering Effect. Nutrients 2024; 16(14).
DOI: 10.3390/nu16142368.
Wu ZY, Song SY, Yu CQ, Sun DJY, Pei P, Du HD et al. Associations of plasma acylcarnitine and
bile acid levels with incidence of coronary heart disease in Chinese adults. Zhonghua Yi Xue Za
Zhi 2024; 104(46):4204–11. DOI: 10.3760/cma.j.cn112137-20240626-01428.
2023
Avery EG, Bartolomaeus H, Rauch A, Chen C-Y, N'Diaye G, Löber U et al. Quantifying the impact
of gut microbiota on inflammation and hypertensive organ damage. Cardiovascular Research
2023; 119(6):1441–52. DOI: 10.1093/cvr/cvac121.
Berkowicz P, Totoń-Żurańska J, Kwiatkowski G, Jasztal A, Csípő T, Kus K et al. Accelerated
ageing and coronary microvascular dysfunction in chronic heart failure in Tgαq*44 mice.
GeroScience 2023:1–30. DOI: 10.1007/s11357-022-00716-y.
Dieu X, Tamareille S, Herbreteau A, Lebeau L, La Chao de Barca JM, Chabrun F et al. Combined
Metabolipidomic and Machine Learning Approach in a Rat Model of Stroke Reveals a
Deleterious Impact of Brain Injury on Heart Metabolism. IJMS 2023 [cited 2023 Jul 27];
24(15):12000. DOI: 10.3390/ijms241512000.
Doppler C, Messner B, Mimler T, Schachner B, Rezk M, Ganhör C et al. Non-canonical
atherosclerosis as the driving force in tricuspid aortic valve associated aneurysms - a trace
collection. Journal of Lipid Research 2023:100338. DOI: 10.1016/j.jlr.2023.100338.
Krause J, Nickel A, Madsen A, Aitken-Buck HM, Stoter AMS, Schrapers J et al. An arrhythmogenic
metabolite in atrial fibrillation. J Transl Med 2023; 21(1):566.
DOI: 10.1186/s12967-023-04420-z.
Lee E-J, Da Kim J, Kang D-W, Yang W, Jeong H-Y, Kim J-M et al. Targeted Metabolomic
Biomarkers for Stroke Subtyping. Transl Stroke Res 2023. DOI: 10.1007/s12975-023-01137-5.
Morici N, Frigerio G, Campolo J, Fustinoni S, Sacco A, Garatti L et al. Cardiogenic Shock
Integrated PHenotyping for Event Reduction: A Pilot Metabolomics Analysis. IJMS 2023;
24(24):17607. DOI: 10.3390/ijms242417607.
Wiese S, Danielsen KV, Busk T, Hove JD, Ytting H, Hansen SH et al. Altered serum bile acid
composition is associated with cardiac dysfunction in cirrhosis. Aliment Pharmacol Ther 2023;
58(4):453–62. DOI: 10.1111/apt.17533.
2022
Bekfani T, Bekhite M, Neugebauer S, Derlien S, Hamadanchi A, Nisser J et al. Metabolomic
Profiling in Patients with Heart Failure and Exercise Intolerance: Kynurenine as a Potential
Biomarker. Cells 2022; 11(10):1674. DOI: 10.3390/cells11101674.
Bollen Pinto B, Ferrario M, Herpain A, Brunelli L, Bendjelid K, Carrara M et al. Metabolites
Concentration in Plasma and Heart Tissue in Relation to High Sensitive Cardiac Troponin T Level
in Septic Shock Pigs. Metabolites 2022; 12(4):319. DOI: 10.3390/metabo12040319.
biocrates-List of publications (Q4-2024)
For research use only | not for use in diagnostic procedures
page 4
Cansby E, Kumari S, Caputo M, Xia Y, Porosk R, Robinson J et al. Silencing of STE20-type kinase
STK25 in human aortic endothelial and smooth muscle cells is atheroprotective. Commun Biol
2022; 5(1):379. DOI: 10.1038/s42003-022-03309-9.
Cheng P, Han H, Chen F, Cheng L, Ma C, Huang H et al. Amelioration of acute myocardial
infarction injury through targeted ferritin nanocages loaded with an ALKBH5 inhibitor. Acta
Biomater 2022; 140:481–91. DOI: 10.1016/j.actbio.2021.11.041.
Eerik K, Kasepalu T, Kuusik K, Eha J, Vähi M, Kilk K et al. Effects of RIPC on the Metabolome in
Patients Undergoing Vascular Surgery: A Randomized Controlled Trial. Biomolecules 2022;
12(9):1312. DOI: 10.3390/biom12091312.
Facchinello N, Astone M, Audano M, Oberkersch RE, Spizzotin M, Calura E et al. Oxidative
pentose phosphate pathway controls vascular mural cell coverage by regulating extracellular
matrix composition. Nat Metab 2022; 4(1):123–40. DOI: 10.1038/s42255-021-00514-4.
Haghikia A, Zimmermann F, Schumann P, Jasina A, Roessler J, Schmidt D et al. Propionate
attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol
metabolism. Eur Heart J 2022; 43(6):518–33. DOI: 10.1093/eurheartj/ehab644.
Hassan L, Efremov L, Großkopf A, Kartschmit N, Medenwald D, Schott A et al. Cardiovascular
risk factors, living and ageing in Halle: the CARLA study. Eur J Epidemiol 2022; 37(1):103–16.
DOI: 10.1007/s10654-021-00824-7.
Hofbauer TM, Distelmaier K, Muqaku B, Spinka G, Seidl V, Arfsten HT et al. Metabolomics
implicate eicosanoids in severe functional mitral regurgitation. ESC Heart Failure 2022.
DOI: 10.1002/ehf2.14160.
Hsu P-C, Maity S, Patel J, Lupo PJ, Nembhard WN. Metabolomics Signatures and Subsequent
Maternal Health among Mothers with a Congenital Heart Defect-Affected Pregnancy.
Metabolites 2022; 12(2):100. DOI: 10.3390/metabo12020100.
Huang C-C, Huang Y-L, Lin C-H, Chen J-W. Plasma metabolomic profiles associated with
hypertension and blood pressure in response to thiazide diuretics. Hypertens Res 2022;
45(3):464–73. DOI: 10.1038/s41440-021-00825-9.
La Chao de Barca JM, Chabrun F, Lefebvre T, Roche O, Huetz N, Blanchet O et al. A
Metabolomic Profiling of Intra-Uterine Growth Restriction in Placenta and Cord Blood Points to
an Impairment of Lipid and Energetic Metabolism. Biomedicines 2022; 10(6).
DOI: 10.3390/biomedicines10061411.
Lee Y-H, Park S. Genetic and Lifestyle-Related Factors Influencing Serum HyperPropionylcarnitine Concentrations and Their Association with Metabolic Syndrome and
Cardiovascular Disease Risk. IJMS 2023; 24(21):15810. DOI: 10.3390/ijms242115810.
Loretz N, Becker C, Hochstrasser S, Metzger K, Beck K, Mueller J et al. Activation of the
kynurenine pathway predicts mortality and neurological outcome in cardiac arrest patients: A
validation study. J Crit Care 2022; 67:57–65. DOI: 10.1016/j.jcrc.2021.09.025.
Reel S, Reel PS, Erlic Z, Amar L, Pecori A, Larsen CK et al. Predicting Hypertension Subtypes with
Machine Learning Using Targeted Metabolites and Their Ratios. Metabolites 2022; 12(8):755.
DOI: 10.3390/metabo12080755.
Reel PS, Reel S, van Kralingen JC, Langton K, Lang K, Erlic Z et al. Machine learning for
classification of hypertension subtypes using multi-omics: A multi-centre, retrospective, datadriven study. EBioMedicine 2022; 84:104276. DOI: 10.1016/j.ebiom.2022.104276.
biocrates-List of publications (Q4-2024)
For research use only | not for use in diagnostic procedures
page 5
Zalesak-Kravec S, Huang W, Jones JW, Yu J, Alloush J, Defnet AE et al. Role of cellular retinolbinding protein, type 1 and retinoid homeostasis in the adult mouse heart: A multi-omic
approach. FASEB J. 2022; 36(4). DOI: 10.1096/fj.202100901RRR.
2021
Baraniuk JN, Kern G, Narayan V, Cheema A. Exercise modifies glutamate and other metabolic
biomarkers in cerebrospinal fluid from Gulf War Illness and Myalgic encephalomyelitis / Chronic
Fatigue Syndrome. PLOS ONE 2021; 16(1):e0244116. DOI: 10.1371/journal.pone.0244116.
Bartenbach L, Karall T, Koch J, Keller MA, Oberacher H, Scholl-Bürgi S et al. Amino Acid and
Phospholipid Metabolism as an Indicator of Inflammation and Subtle Cardiomyopathy in
Patients with Marfan Syndrome. Metabolites 2021; 11(12). DOI: 10.3390/metabo11120805.
Bouche L, Kamel R, Tamareille S, Garcia G, Villedieu C, Pillot B et al. DRP1 haploinsufficiency
attenuates cardiac ischemia/reperfusion injuries. PLOS ONE 2021; 16(3):e0248554.
DOI: 10.1371/journal.pone.0248554.
Cedars A, Manlhiot C, Ko J-M, Bottiglieri T, Arning E, Weingarten A et al. Metabolomic Profiling
of Adults with Congenital Heart Disease. Metabolites 2021; 11(8).
DOI: 10.3390/metabo11080525.
Cheng C-W, Liu M-H, Tang H-Y, Cheng M-L, Wang C-H. Factors associated with elevated
plasma phenylalanine in patients with heart failure. Amino Acids 2021; 53(2):149-57.
DOI: 10.1007/s00726-020-02933-1.
Dawczynski C, Cullen PM, Schlattmann P, Lorkowski S. A study protocol of a randomized trial
evaluating the effect of using defined menu plans within an intensive personal nutritional
counseling program on cardiovascular risk factors: The MoKaRi (modulation of cardiovascular
risk factors) trial. Contemp Clin Trials Commun 2021; 22:100761.
DOI: 10.1016/j.conctc.2021.100761.
Emmert DB, Vukovic V, Dordevic N, Weichenberger CX, Losi C, D'Elia Y et al. Genetic and
Metabolic Determinants of Atrial Fibrillation in a General Population Sample: The CHRIS Study.
Biomolecules 2021; 11(11):1663. DOI: 10.3390/biom11111663.
Gladding PA, Loader S, Smith K, Zarate E, Green S, Villas-Boas S et al. Multiomics, virtual reality
and artificial intelligence in heart failure. Future Cardiol 2021; 17(8):1335–47.
DOI: 10.2217/fca-2020-0225.
Haas J, Frese KS, Sedaghat-Hamedani F, Kayvanpour E, Tappu R, Nietsch R et al. Energy
Metabolites as Biomarkers in Ischemic and Dilated Cardiomyopathy. International Journal of
Molecular Sciences 2021; 22(4):1999. DOI: 10.3390/ijms22041999.
Haase D, Bäz L, Bekfani T, Neugebauer S, Kiehntopf M, Möbius-Winkler S et al. Metabolomic
profiling of patients with high gradient aortic stenosis undergoing transcatheter aortic valve
replacement. Clin Res Cardiol 2021; 110(3):399-410. DOI: 10.1007/s00392-020-01754-2.
Hilse MS, Kretzschmar T, Pistulli R, Franz M, Bekfani T, Haase D et al. Analysis of Metabolic
Markers in Patients with Chronic Heart Failure before and after LVAD Implantation. Metabolites
2021; 11(9). DOI: 10.3390/metabo11090615.
Kuka J, Makrecka-Kuka M, Vilks K, Korzh S, Cirule H, Sevostjanovs E et al. Inhibition of Fatty Acid
Metabolism Increases EPA and DHA Levels and Protects against Myocardial IschaemiaReperfusion Injury in Zucker Rats. Oxid Med Cell Longev 2021; 2021:7493190.
DOI: 10.1155/2021/7493190.
biocrates-List of publications (Q4-2024)
For research use only | not for use in diagnostic procedures
page 6
Lehn-Stefan A, Peter A, Machann J, Schick F, Randrianarisoa E, Heni M et al. Elevated
circulating Glutamate associates with subclinical Atherosclerosis independently of established
Risk Markers: a cross-sectional study. J Clin Endocrinol Metab 2021; 106(2):e982-e989.
DOI: 10.1210/clinem/dgaa898.
Lieberg J, Wanhainen A, Ottas A, Vähi M, Zilmer M, Soomets U et al. Metabolomic Profile of
Abdominal Aortic Aneurysm. Metabolites 2021; 11(8). DOI: 10.3390/metabo11080555.
Liepinsh E, Kuka J, Vilks K, Svalbe B, Stelfa G, Vilskersts R et al. Low cardiac content of longchain acylcarnitines in TMLHE knockout mice prevents ischaemia-reperfusion-induced
mitochondrial and cardiac damage. Free Radic Biol Med 2021; 177:370–80.
DOI: 10.1016/j.freeradbiomed.2021.10.035.
Nolde M, Bahls M, Friedrich N, Dörr M, Dreischulte T, Felix SB et al. Association of proton pump
inhibitor use with endothelial function and metabolites of the nitric oxide pathway: A crosssectional study. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
2021; 41(2):198-204. DOI: 10.1002/phar.2504.
O'Connell TM, Logsdon DL, Mitscher G, Payne RM. Metabolic profiles identify circulating
biomarkers associated with heart failure in young single ventricle patients. Metabolomics 2021;
17(10):95. DOI: 10.1007/s11306-021-01846-8.
Piedrafita A, Balayssac S, Mayeur N, Gazut S, Grossac J, Buleon M et al. The tryptophan pathway
and nicotinamide supplementation in ischemic acute kidney injury. Clin Kidney J 2021;
14(12):2490–6. DOI: 10.1093/ckj/sfab050.
Pietzsch S, Wohlan K, Thackeray JT, Heimerl M, Schuchardt S, Scherr M et al. Anthracycline-free
tumor elimination in mice leads to functional and molecular cardiac recovery from cancerinduced alterations in contrast to long-lasting doxorubicin treatment effects. Basic Res Cardiol
2021; 116(1):61. DOI: 10.1007/s00395-021-00902-7.
Portero V, Nicol T, Podliesna S, Marchal GA, Baartscheer A, Casini S et al. Chronically elevated
branched chain amino acid levels are pro-arrhythmic. Cardiovascular Research 2021;
118(7):1742–57. DOI: 10.1093/cvr/cvab207.
Volani C, Rainer J, Hernandes VV, Meraviglia V, Pramstaller PP, Smárason SV et al. Metabolic
Signature of Arrhythmogenic Cardiomyopathy. Metabolites 2021; 11(4).
DOI: 10.3390/metabo11040195.
Zalesak-Kravec S, Huang W, Wang P, Yu J, Liu T, Defnet AE et al. Multi-omic Analysis of Nonhuman Primate Heart after Partial-body Radiation with Minimal Bone Marrow Sparing. Health
Phys 2021; 121(4):352–71. DOI: 10.1097/HP.0000000000001478.
Ziegler D, Strom A, Straßburger K, Knebel B, Bönhof GJ, Kotzka J et al. Association of cardiac
autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2
diabetes. Diabetologia 2021; 64(2):458-68. DOI: 10.1007/s00125-020-05310-5.
1.2
Diabetology
2024
Ahlström FHG, Viisanen H, Karhinen L, Velagapudi V, Blomqvist KJ, Lilius TO et al. Gene
expression in the dorsal root ganglion and the cerebrospinal fluid metabolome in
polyneuropathy and opioid tolerance in rats. IBRO Neuroscience Reports 2024; 17:38–51
DOI: 10.1016/j.ibneur.2024.05.006.
biocrates-List of publications (Q4-2024)
For research use only | not for use in diagnostic procedures
page 7
Bernal-Casas D, Serrano-Marín J, Sánchez-Navés J, Oller JM, Franco R. Advancing Personalized
Medicine by Analytical Means: Selection of Three Metabolites That Allows Discrimination
between Glaucoma, Diabetes, and Controls. Metabolites 2024; 14(3):149
DOI: 10.3390/metabo14030149.
Campos JdO, Oliveira TLPSdA, Vitalis O, Pereira JG, Da Nogueira ICR, Santos GCJ et al.
Association between Childhood Overweight and Altered Concentrations of Circulating Amino
Acids. Nutrients 2024; 16(12) DOI: 10.3390/nu16121843.
Carper D, Lac M, Coue M, Labour A, Märtens A, Banda JAA et al. Loss of atrial natriuretic peptide
signaling causes insulin resistance, mitochondrial dysfunction, and low endurance capacity. Sci
Adv 2024; 10(41):eadl4374. DOI: 10.1126/sciadv.adl4374.
Eriksen R, White MC, Dawed AY, Perez IG, Posma JM, Haid M et al. The association of
cardiometabolic, diet and lifestyle parameters with plasma glucagon-like peptide-1: An IMI
DIRECT study. The Journal of clinical endocrinology and metabolism 2024
DOI: 10.1210/clinem/dgae119.
Golubnitschaja O, Polivka J, Potuznik P, Pesta M, Stetkarova I, Mazurakova A et al. The paradigm
change from reactive medical services to 3PM in ischemic stroke: a holistic approach utilising
tear fluid multi-omics, mitochondria as a vital biosensor and AI-based multi-professional data
interpretation. EPMA J 2024; 15(1):1–23 DOI: 10.1007/s13167-024-00356-6.
Halama A, Zaghlool S, Thareja G, Kader S, Al Muftah W, Mook-Kanamori M et al. A roadmap to
the molecular human linking multiomics with population traits and diabetes subtypes. Nat
Commun 2024; 15(1):7111. DOI: 10.1038/s41467-024-51134-x.
Kryska A, Depciuch J, Krysa M, Paja W, Wosiak A, Nicoś M et al. Lipids balance as a
spectroscopy marker of diabetes. Analysis of FTIR spectra by 2D correlation and machine
learning analyses. Spectrochim Acta A Mol Biomol Spectrosc 2024; 320:124653
DOI: 10.1016/j.saa.2024.124653.
Kuo H-C, Lin C-N, Tsai S-S, Chen C-M, Lyu R-K, Chu C-C et al. Blood metabolomic profile in
patients with type 2 diabetes mellitus with diabetic peripheral neuropathic pain. J Diabetes
Investig 2025; 16(2):246–56. DOI: 10.1111/jdi.14355.
Lai M, Li J, Yang J, Zhang Q, Gong Y, Ma Y et al. Metabolomic profiling reveals decreased serum
cysteine levels during gestational diabetes mellitus progression. J Mol Cell Biol 2024; 16(3).
DOI: 10.1093/jmcb/mjae010.
Lamacchia O, Menzaghi C, Copetti M, Mastroianno M, Corsano C, Prehn C et al. GFR decline
predicts total mortality and mediates the effect of tryptophan metabolism on death risk in type
2 diabetes. J. Clin. Endocrinol. Metab. 2024. DOI: 10.1210/clinem/dgae551.
Leiherer A, Muendlein A, Mink S, Mader A, Saely CH, Festa A et al. Machine Learning Approach
to Metabolomic Data Predicts Type 2 Diabetes Mellitus Incidence. International Journal of
Molecular Sciences 2024; 25(10) DOI: 10.3390/ijms25105331.
Mah MS, Cao E, Anderson D, Escott A, Tegegne S, Gracia G et al. High-fat feeding drives the
intestinal production and assembly of C16:0 ceramides in chylomicrons. Sci Adv 2024;
10(34):eadp2254. DOI: 10.1126/sciadv.adp2254.
biocrates-List of publications (Q4-2024)
For research use only | not for use in diagnostic procedures
page 8
Myrmel LS, Fjære E, Han M, Jensen BAH, Rolle-Kampczyk U, Danneskiold-Samsøe NB et al. The
Food Sources in Western Diets Modulate Obesity Development, Insulin Sensitivity, and the
Plasma and Cecal Metabolome in Mice. Mol Nutr Food Res 2024; 68(16):e2400246.
DOI: 10.1002/mnfr.202400246.
Menzaghi C, Marucci A, Mastroianno M, Di Ciaccia G, Armillotta MP, Prehn C et al.
Inflammation and prediction of death in type 2 diabetes. Evidence of an intertwined link with
tryptophan metabolism. J. Clin. Endocrinol. Metab. 2024. DOI: 10.1210/clinem/dgae593.
Ott H, Bennewitz K, Zhang X, Prianichnikova M, Sticht C, Poschet G et al. Sodium thiosulfate
treatment rescues hyperglycaemia-induced pronephros damage in zebrafish by upregulating
nitric oxide signalling. J Physiol 2024. DOI: 10.1113/JP286398.
Raeisi-Dehkordi H, Thorand B, Beigrezaei S, Peters A, Rathman W, Adamski J et al. The
mediatory role of androgens on sex differences in glucose homeostasis and incidence of type 2
diabetes: the KORA study. Cardiovasc Diabetol 2024; 23(1):411. DOI: 10.1186/s12933-02402494-7.
Ratter-Rieck JM, Shi M, Suhre K, Prehn C, Adamski J, Rathmann W et al. Omentin associates with
serum metabolite profiles indicating lower diabetes risk: KORA F4 Study. BMJ Open Diabetes
Research and Care 2024; 12(2):e003865 DOI: 10.1136/bmjdrc-2023-003865.
Sarkar P, Chintaluri S, Sarkar S, Unnisa M, Jakkampudi A, Mulukutla AP et al. Evaluation of the
Crosstalk Between the Host Mycobiome and Bacteriome in Patients with Chronic Pancreatitis.
Indian J Microbiol 2024:1–15 DOI: 10.1007/s12088-024-01207-8.
Sharma S, Dong Q, Haid M, Adam J, Bizzotto R, Fernandez-Tajes JJ et al. Role of human plasma
metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study. Diabetologia 2024;
67(12):2804–18. DOI: 10.1007/s00125-024-06282-6.
Spagnolo P, Tweddell D, Cela E, Daley M, Clarson C, Rupar CA et al. Metabolomic signature of
pediatric diabetic ketoacidosis: key metabolites, pathways, and panels linked to clinical
variables. Mol Med 2024; 30(1):250. DOI: 10.1186/s10020-024-01046-9.
Trischitta V, Antonucci A, Menzaghi C, Marucci A, Di Paola R. GALNT2 expression is associated
with glucose control and serum metabolites in patients with type 2 diabetes. Acta Diabetol
2024:1–7 DOI: 10.1007/s00592-024-02280-7.
Varkevisser RDM, Cecil A, Prehn C, Mul D, Aanstoot HJ, Paterson AD et al. Metabolomic
associations of impaired awareness of hypoglycaemia in type 1 diabetes. Sci Rep 2024;
14(1):4485. DOI: 10.1038/s41598-024-55032-6.
2023
Abu-Farha M, Joseph S, Mohammad A, Channanath A, Taher I, Al-Mulla F et al. Targeted
Metabolomics Analysis of Individuals Carrying the ANGPTL8 R59W Variant. Metabolites 2023;
13(9):972. DOI: 10.3390/metabo13090972.
Anwardeen NR, Cyprian FS, Yassine HM, Al-Thani AA, Abdallah AM, Emara MM et al. The
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6.5
Gastroenterology
2024
Sarkar P, Chintaluri S, Sarkar S, Unnisa M, Jakkampudi A, Mulukutla AP et al. Evaluation of the
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Pietzner M, Budde K, Rühlemann M, Völzke H, Homuth G, Weiss FU et al. Exocrine Pancreatic
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6.6
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2024
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2023
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Huang J, Liu M, Furey A, Rahman P, Zhai G. Gut Microbiomics of Sustained Knee Pain in Patients
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Jo A, Kim K-S, Won J, Shin H, Kim S, Kim B et al. Nasal symbiont Staphylococcus epidermidis
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Kipele M, Buchfelder M, Taudte RV, Stadlbauer A, Kinfe T, Bozhkov Y. Immunometabolic
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Mehta O, Vijay A, Gohir SA, Kelly T, Zhang W, Doherty M et al. Serum Metabolome Analysis
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MA et al. Immunometabolic actions of trabectedin and lurbinectedin on human macrophages:
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Przespolewski AC, Rosario S, Hsiao H-H, Rutland N, McSain S, Cronin T et al. Newly Diagnosed
AML Exhibits Significant Differences in Immune Metabolic Pathways and Inflammatory States in
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Sato S, Watanabe S, Saito Y, Takanashi A, Ikeda H, Sakurai Y et al. High Expression of Adrenal
Cortisol Synthases Is Acquired After Intrauterine Inflammation in Periviable Sheep Fetuses. J.
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Urbanski G, Chabrun F, Delattre E, Lacout C, Davidson B, Blanchet O et al. An immunolipidomic signature revealed by metabolomic and machine-learning approaches in labial
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West EE, Merle NS, Kamiński MM, Palacios G, Kumar D, Wang L et al. Loss of CD4+ T cellintrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during
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2022
Alfarano G, Audano M, Di Chiaro P, Balestrieri C, Milan M, Polletti S et al. Interferon regulatory
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Billiet B, La Chao de Barca JM, Ferré M, Muller J, Vautier A, Assad S et al. A Tear Metabolomic
Profile Showing Increased Ornithine Decarboxylase Activity and Spermine Synthesis in ThyroidAssociated Orbitopathy. JCM 2022; 11(2):404. DOI: 10.3390/jcm11020404.
Chen F, Elgaher WAM, Winterhoff M, Büssow K, Waqas FH, Graner E et al. Citraconate inhibits
ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates
inflammation and cell metabolism. Nat Metab 2022; 4(5):534–46.
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Franck M, Toro-Martín J de, Varin TV, Garneau V, Pilon G, Roy D et al. Raspberry consumption:
identification of distinct immune-metabolic response profiles by whole blood transcriptome
profiling. The Journal of Nutritional Biochemistry 2022; 101:108946.
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Galler AI, Klavins K, Burgener IA. A Preliminary Metabolomic Study of Yorkshire Terrier
Enteropathy. Metabolites 2022; 12(3). DOI: 10.3390/metabo12030264.
Gupta A, Galinski MR, Voit EO. Dynamic Control Balancing Cell Proliferation and Inflammation
is Crucial for an Effective Immune Response to Malaria. Front. Mol. Biosci. 2022; 8.
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Ilves L, Ottas A, Kaldvee B, Abram K, Soomets U, Zilmer M et al. Metabolomic Differences
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Kang J, Kim JY, Jung Y, Kim SU, Lee EY, Cho J-Y. Identification of Metabolic Signature Associated
with Idiopathic Inflammatory Myopathy Reveals Polyamine Pathway Alteration in Muscle Tissue.
Metabolites 2022; 12(10):1004. DOI: 10.3390/metabo12101004.
Liu M, Zhang H, Xie Z, Huang Y, Sun G, Qi D et al. Glutathione, polyamine, and
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Macchi C, Moregola A, Greco M, Svecla M, Bonacina F, Dhup S et al. Monocarboxylate
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Manka P, Sydor S, Schänzer-Ocklenburg JM, Brandenburg M, Best J, Vilchez-Vargas R et al. A
Potential Role for Bile Acid Signaling in Celiac Disease-Associated Fatty Liver. Metabolites 2022;
12(2):130. DOI: 10.3390/metabo12020130.
Mohammed AD, Mohammed Z, Roland MM, Chatzistamou I, Jolly A, Schoettmer LM et al.
Defective humoral immunity disrupts bile acid homeostasis which promotes inflammatory
disease of the small bowel. Nat Commun 2022; 13(1):525. DOI: 10.1038/s41467-022-28126-w.
Rabelo IB, Chiba AK, Moritz E, D'Amora P, Silva IDCG, Rodrigues CA et al. Metabolomic profile
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Rockel JS, Layeghifard M, Rampersaud YR, Perruccio AV, Mahomed NN, Davey JR et al.
Identification of a differential metabolite-based signature in patients with late-stage knee
osteoarthritis. Osteoarthritis and Cartilage Open 2022; 4(3):100258.
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Trovato FM, Mujib S, Jerome E, Cavazza A, Morgan P, Smith J et al. Immunometabolic analysis
shows a distinct cyto-metabotype in Covid-19 compared to sepsis from other causes. Heliyon
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Trovato FM, Zia R, Artru F, Mujib S, Jerome E, Cavazza A et al. Lysophosphatidylcholines
modulate immunoregulatory checkpoints in peripheral monocytes and are associated with
mortality in people with acute liver failure. Journal of Hepatology 2022.
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Waqas SF-U-H, Sohail A, Nguyen AHH, Usman A, Ludwig T, Wegner A et al. ISG15 deficiency
features a complex cellular phenotype that responds to treatment with itaconate and
derivatives. Clin Transl Med 2022; 12(7):e931. DOI: 10.1002/ctm2.931.
Wen B, Njunge JM, Bourdon C, Gonzales GB, Gichuki BM, Lee D et al. Systemic inflammation
and metabolic disturbances underlie inpatient mortality among ill children with severe
malnutrition. Science Advances 2022; 8(7). DOI: 10.1126/sciadv.abj6779.
Zhang G, Tobolski D, Zwierzchowski G, Mandal R, Wishart DS, Ametaj BN. Identification of
Serum-Predictive Biomarkers for Subclinical Mastitis in Dairy Cows and New Insights into the
Pathobiology of the Disease. Journal of Agricultural and Food Chemistry 2022; 70(5):1724–46.
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2021
Baraniuk JN, Kern G, Narayan V, Cheema A. Exercise modifies glutamate and other metabolic
biomarkers in cerebrospinal fluid from Gulf War Illness and Myalgic encephalomyelitis / Chronic
Fatigue Syndrome. PLOS ONE 2021; 16(1):e0244116. DOI: 10.1371/journal.pone.0244116.
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Bäßler SC, Kenéz Á, Scheu T, Koch C, Meyer U, Dänicke S et al. Association between alterations
in plasma metabolome profiles and laminitis in intensively finished Holstein bulls in a
randomized controlled study. Sci Rep 2021; 11(1):12735. DOI: 10.1038/s41598-021-92163-6.
Caterino M, Gelzo M, Sol S, Fedele R, Annunziata A, Calabrese C et al. Dysregulation of lipid
metabolism and pathological inflammation in patients with COVID-19. Sci Rep 2021;
11(1):2941. DOI: 10.1038/s41598-021-82426-7.
da Silva IDCG, Marchioni DML, Carioca AAF, Bueno V, Colleoni GWB. May critical molecular
cross-talk between indoleamine 2,3-dioxygenase (IDO) and arginase during human aging be
targets for immunosenescence control? Immun Ageing 2021; 18(1):33.
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Delarocque J, Reiche DB, Meier AD, Warnken T, Feige K, Sillence MN. Metabolic profile
distinguishes laminitis-susceptible and -resistant ponies before and after feeding a high sugar
diet. BMC Vet Res 2021; 17(1):56. DOI: 10.1186/s12917-021-02763-7.
Fernandez-Guerra P, Gonzalez-Ebsen AC, Boonen SE, Courraud J, Gregersen N, Mehlsen J et al.
Bioenergetic and Proteomic Profiling of Immune Cells in Myalgic Encephalomyelitis/Chronic
Fatigue Syndrome Patients: An Exploratory Study. Biomolecules 2021; 11(7):961.
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Ferrario M, Pastorelli R, Brunelli L, Liu S, Zanella do Amaral Campos PP, Casoni D et al.
Persistent hyperammonia and altered concentrations of urea cycle metabolites in a 5-day swine
experiment of sepsis. Sci Rep 2021; 11(1):18430. DOI: 10.1038/s41598-021-97855-7.
Furrer R, Jauch AJ, Nageswara Rao T, Dilbaz S, Rhein P, Steurer SA et al. Remodeling of
metabolism and inflammation by exercise ameliorates tumor-associated anemia. Science
Advances 2021; 7(37):eabi4852. DOI: 10.1126/sciadv.abi4852.
Ilves L, Ottas A, Kaldvee B, Abram K, Soomets U, Zilmer M et al. Metabolomic Analysis of Skin
Biopsies from Patients with Atopic Dermatitis Reveals Hallmarks of Inflammation, Disrupted
Barrier Function and Oxidative Stress. Acta Derm Venereol 2021; 101(2):adv00407.
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Liu M, Xie Z, Costello CA, Zhang W, Chen L, Qi D et al. Metabolomic analysis coupled with
extreme phenotype sampling identified that lysophosphatidylcholines are associated with
multisite musculoskeletal pain. Pain 2021; 162(2):600-8.
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Ma L, Nidadavolu LS, Yang H, Langdon J, Westbrook R, Tsui BMW et al. Targeted deletion of
interleukin-6 in a mouse model of chronic inflammation demonstrates opposing roles in aging:
benefit and harm. J Gerontol A Biol Sci Med Sci 2021; 76(2):211-5.
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Palma C, La Rocca C, Gigantino V, Aquino G, Piccaro G, Di Silvestre D et al. Caloric Restriction
Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis. Cell
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Patterson GT, Manthi D, Osuna F, Muia A, Olack B, Mbuchi M et al. Environmental, Metabolic,
and Inflammatory Factors Converge in the Pathogenesis of Moderate Acute Malnutrition in
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Paul JC, Yilmaz A, Pieper BA, Liu Z, Graham SF. Prospective comparative study: metabolomics
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Inflammation and Necrosis Syndrome Is Associated with Plasma Metabolites and Liver
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Rubio T, Felipo V, Tarazona S, Pastorelli R, Escudero-García D, Tosca J et al. Multi-omic analysis
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Tarazona S, Carmona H, Conesa A, Llansola M, Felipo V. A multi-omic study for uncovering
molecular mechanisms associated with hyperammonemia-induced cerebellar function
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Werdyani S, Liu M, Zhang H, Sun G, Furey A, Randell EW et al. Endotypes of primary
osteoarthritis identified by plasma metabolomics analysis. Rheumatology (Oxford) 2021;
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Xu B, Su H, Wang R, Wang Y, Zhang W. Metabolic networks of plasma and joint fluid base on
differential correlation. PLoS One 2021; 16(2):e0247191. DOI: 10.1371/journal.pone.0247191.
6.9
Methodology
2024
Canzler S, Schubert K, Rolle-Kampczyk UE, Wang Z, Schreiber S, Seitz H et al. Evaluating the
performance of multi-omics integration: a thyroid toxicity case study. Arch Toxicol 2025;
99(1):309–32. DOI: 10.1007/s00204-024-03876-2.
Hagn G, Meier-Menches SM, Plessl-Walder G, Mitra G, Mohr T, Preindl K et al. Plasma Instead of
Serum Avoids Critical Confounding of Clinical Metabolomics Studies by Platelets. J. Proteome
Res. 2024 DOI: 10.1021/acs.jproteome.3c00761.
2023
Brown AA, Fernandez-Tajes JJ, Hong M-G, Brorsson CA, Koivula RW, Davtian D et al. Genetic
analysis of blood molecular phenotypes reveals common properties in the regulatory networks
affecting complex traits. Nat Commun 2023; 14(1):5062. DOI: 10.1038/s41467-023-40569-3.
Bovo S, Schiavo G, Galimberti G, Fanelli F, Bertolini F, Dall'Olio S et al. Comparative targeted
metabolomic profiles of porcine plasma and serum. Animal 2023; 17(12):101029.
DOI: 10.1016/j.animal.2023.101029.
Godlewski A, Czajkowski M, Mojsak P, Pienkowski T, Gosk W, Lyson T et al. A comparison of
different machine-learning techniques for the selection of a panel of metabolites allowing early
detection of brain tumors. Sci Rep 2023; 13(1):11044. DOI: 10.1038/s41598-023-38243-1.
Greimel A, Habler K, Gräfe C, Maciuga N, Brozat CI, Vogeser M et al. Extracorporeal adsorption
of protective and toxic bile acids and bilirubin in patients with cholestatic liver dysfunction: a
prospective study. Ann. Intensive Care 2023; 13(1):110. DOI: 10.1186/s13613-023-01198-7.
Gupta S, Gormley IC, Brennan L. MetaboVariation: Exploring Individual Variation in Metabolite
Levels. Metabolites 2023; 13(2):164. DOI: 10.3390/metabo13020164.
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Pawliszyn J, Jiang RW, Jaroch K. Solid-phase microextraction of endogenous metabolites from
intact tissue validated using a Biocrates standard reference method kit. Journal of
Pharmaceutical Analysis 2023; 13(1):55–62. DOI: 10.1016/j.jpha.2022.09.002.
Pietrowska K, Godlewski A, Grochowski E, Gosk W, Konopinska J, Kretowski A et al. Adaptation
of the AbsoluteIDQ p180 kit to the analysis of metabolites in the human aqueous humor. J
Chromatogr B Analyt Technol Biomed Life Sci 2023; 1229:123880.
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Psomas A, Chowdhury NR, Middleton B, Winsky-Sommerer R, Skene DJ, Gerkema MP et al. Coexpression of diurnal and ultradian rhythms in the plasma metabolome of common voles
(Microtus arvalis). The FASEB Journal 2023; 37(4):e22827. DOI: 10.1096/fj.202201585R.
Santucci L, Lomuscio S, Primiano A, Calvani R, Persichilli S, Iavarone F et al. Development of a
novel Ultra Performance Liquid Chromatography Tandem-Mass Spectrometry (UPLC-MS/MS)
method to measure l-arginine metabolites in plasma. Clin Chim Acta 2023; 543:117306.
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Sun T-H, Wang C-C, Wu Y-L, Hsu K-C, Lee T-H. Machine learning approaches for biomarker
discovery to predict large-artery atherosclerosis. Sci Rep 2023; 13(1):15139.
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Woelders T, Revell VL, Middleton B, Ackermann K, Kayser M, Raynaud FI et al. Machine learning
estimation of human body time using metabolomic profiling. Proc Natl Acad Sci U S A 2023;
120(18):e2212685120. DOI: 10.1073/pnas.2212685120.
2022
Artati A, Prehn C, Lutter D, Dyar KA. Untargeted and Targeted Circadian Metabolomics Using
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) and Flow InjectionElectrospray Ionization-Tandem Mass Spectrometry (FIA-ESI-MS/MS). In: Solanas G, Welz P-S,
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Daisuke Saigusa, Takeshi Honda, Yuko Iwasaki, Koji Ueda, Eiji Hishinuma, Naomi Matsukawa et
al. Lipidomic and metabolic profiling of plasma and plasma-derived extracellular vesicles by
UHPLC-MS/MS. MMS 2022; 6(2):126–37. DOI: 10.24508/mms.2022.11.007.
Fritsche-Guenther R, Gloaguen Y, Eisenberger A, Kirwan JA. Analysis of adherent cell culture
lysates with low metabolite concentrations using the Biocrates AbsoluteIDQ p400 HR kit. Sci
Rep 2022; 12(1):7933. DOI: 10.1038/s41598-022-11118-7.
Haange S-B, Till A, Bergh P-O, Fauler G, Gigl M, Löfgren-Sandblom A et al. Ring Trial on
Quantitative Assessment of Bile Acids Reveals a Method- and Analyte-Specific Accuracy and
Reproducibility. Metabolites 2022; 12(7):583. DOI: 10.3390/metabo12070583.
Howard J, Wynne K, Moldenhauer E, Clarke P, Maguire C, Bollard S et al. A comparative analysis
of extracellular vesicles (EVs) from human and feline plasma. Sci Rep 2022; 12(1):10851.
DOI: 10.1038/s41598-022-14211-z.
Gloaguen Y, Kirwan JA, Beule D. Deep Learning-Assisted Peak Curation for Large-Scale LC-MS
Metabolomics. Anal. Chem. 2022; 94(12):4930–7. DOI: 10.1021/acs.analchem.1c02220.
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Ivanova L, Rangel-Huerta OD, Tartor H, Gjessing MC, Dahle MK, Uhlig S. Fish Skin and Gill
Mucus: A Source of Metabolites for Non-Invasive Health Monitoring and Research. Metabolites
2022; 12(1):28. DOI: 10.3390/metabo12010028.
Morabito A, Simone G de, Ferrario M, Falcetta F, Pastorelli R, Brunelli L. EASY-FIA: A Readably
Usable Standalone Tool for High-Resolution Mass Spectrometry Metabolomics Data PreProcessing. Metabolites 2023; 13(1):13. DOI: 10.3390/metabo13010013.
Pereira J, Bresser LRF, van Riel N, Looijesteijn E, Schoemaker R, Ulfman LH et al. Bovine Milk Fat
Intervention in Early Life and Its Impact on Microbiota, Metabolites and Clinical Phenotype: A
Multi-Omics Stacked Regularization Approach. BioMedInformatics 2022; 2(2):281–96.
DOI: 10.3390/biomedinformatics2020018.
Schoeny H, Rampler E, Binh Chu D, Schoeberl A, Galvez L, Blaukopf M et al. Achieving Absolute
Molar Lipid Concentrations: A Phospholipidomics Cross-Validation Study. Analytical Chemistry
2022; 94(3):1618–25. DOI: 10.1021/acs.analchem.1c03743.
Yamakawa M, Karashima S, Takata R, Haba T, Kuroiwa K, Touyama H et al. Comprehensive
Steroid Assay with Non-Targeted Analysis Using Liquid Chromatography Ion Mobility Mass
Spectrometry. IJMS 2022; 23(22):13858. DOI: 10.3390/ijms232213858.
2021
Baddam P, Biancardi V, Roth DM, Eaton F, Thereza-Bussolaro C, Mandal R et al. Neural crestspecific deletion of Bmp7 leads to midfacial hypoplasia, nasal airway obstruction, and
disordered breathing modelling Obstructive Sleep Apnea. Dis Model Mech 2021;
14(2):dmm047738. DOI: 10.1242/dmm.047738.
Chaby LE, Lasseter HC, Contrepois K, Salek RM, Turck CW, Thompson A et al. Cross-Platform
Evaluation of Commercially Targeted and Untargeted Metabolomics Approaches to Optimize
the Investigation of Psychiatric Disease. Metabolites 2021; 11(9).
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Erben V, Poschet G, Schrotz-King P, Brenner H. Evaluation of different stool extraction methods
for metabolomics measurements in human faecal samples. BMJ Nutr Prev Health 2021;
4(2):374–84. DOI: 10.1136/bmjnph-2020-000202.
Neuberger-Castillo L, Ammerlaan W, Betsou F. Fitness for purpose of stabilized stool samples
for bile acid metabolite analyses. Sci Rep 2021; 11(1):7904. DOI: 10.1038/s41598-021-86784-0.
Saigusa D, Hishinuma E, Matsukawa N, Takahashi M, Inoue J, Tadaka S et al. Comparison of KitBased Metabolomics with Other Methodologies in a Large Cohort, towards Establishing
Reference Values. Metabolites 2021; 11(10). DOI: 10.3390/metabo11100652.
Schmidt JA, Fensom GK, Rinaldi S, Scalbert A, Gunter MJ, Holmes MV et al. NMR Metabolite
Profiles in Male Meat-Eaters, Fish-Eaters, Vegetarians and Vegans, and Comparison with MS
Metabolite Profiles. Metabolites 2021; 11(2):121. DOI: 10.3390/metabo11020121.
Sutton CM, Springman SA, Abedal-Majed MA, Cupp AS. Bovine Ovarian Cortex Tissue Culture.
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6.10 Microbiome
2024
Duysburgh C, Govaert M, Guillemet D, Marzorati M. Co-Supplementation of Baobab Fiber and
Arabic Gum Synergistically Modulates the In Vitro Human Gut Microbiome Revealing
Complementary and Promising Prebiotic Properties. Nutrients 2024; 16(11)
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Essex M, Millet Pascual-Leone B, Löber U, Kuhring M, Zhang B, Brüning U et al. Gut microbiota
dysbiosis is associated with altered tryptophan metabolism and dysregulated inflammatory
response in COVID-19. NPJ Biofilms Microbiomes 2024; 10(1):66. DOI: 10.1038/s41522-02400538-0.
Heumel S, Rezende Rodovalho V de, Urien C, Specque F, Brito Rodrigues P, Robil C et al.
Shotgun metagenomics and systemic targeted metabolomics highlight indole-3-propionic acid
as a protective gut microbial metabolite against influenza infection. Gut Microbes 2024;
16(1):2325067 DOI: 10.1080/19490976.2024.2325067.
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