2026 · Nucleic acids research · Oxford University Press · added 2026-04-21
Biomedical research benefits from the rapid growth and diversity of experimentally detected protein–protein interactions (PPIs) by gaining important biological insights. However, increasingly dense PP Show more
Biomedical research benefits from the rapid growth and diversity of experimentally detected protein–protein interactions (PPIs) by gaining important biological insights. However, increasingly dense PPI networks can be challenging to interpret and apply. The 2025 update of the Integrated Interactions Database (IID) enhances accessibility and utility through several new features. We identify and incorporate network structural components from co-purified protein sets, as well as curated and predicted complexes, enabling users to explore network organization Show less