2025 · Cui et al. BioData Mining · BioMed Central · added 2026-04-21
Deep learning, a cornerstone of artificial intelligence, is driving rapid advancements in computational biology. Protein-protein interactions (PPIs) are fundamental regulators of biological functions. Show more
Deep learning, a cornerstone of artificial intelligence, is driving rapid advancements in computational biology. Protein-protein interactions (PPIs) are fundamental regulators of biological functions. With the inclusion of deep learning in PPI research, the field is undergoing transformative changes. Therefore, there is an urgent need for a comprehensive review and assessment of recent developments to improve analytical methods and open up a wider range of biomedical applications. This review meticulously assesses deep learning progress in PPI prediction from 2021 Show less